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HSC Stuff => HSC Science Stuff => HSC Subjects + Help => HSC Biology => Topic started by: Sa1998 on July 12, 2016, 09:35:51 pm

Title: Protein synthesis
Post by: Sa1998 on July 12, 2016, 09:35:51 pm
I always mix this process up. Please help!!!!
Much appreciated.
Title: Re: Protein synthesis
Post by: vox nihili on July 13, 2016, 11:54:21 am
I always mix this process up. Please help!!!!
Much appreciated.

Tell us what you know first so we can see where you're at
Title: Re: Protein synthesis
Post by: naomisirmai on July 13, 2016, 08:14:17 pm
Transcription: DNA -> mRNA
1. DNA unwinds and unzips
2. RNA polymerase links complementary RNA nucleotides to the unwound DNA – forming an mRNA strand
3. mRNA strand is modified so that it contains only exons (regions that code for proteins)
4. mRNA moves from the nucleus of the cell into the cytoplasm[/li][/list]

Translation: mRNA + tRNA -> polypeptide -> protein
5. mRNA binds to a ribosome
6. tRNA carrying anticodons binds to mRNA’s codons
7. A polypeptide chain is formed until a ’stop’ codon is reached
8. Newly formed polypeptide chain is released into the cytoplasm

It always occurs in this order. If you have faulty or mutated DNA, you'll end up with a different polypeptide produced!

Does this all make sense?

Title: Re: Protein synthesis
Post by: jamonwindeyer on July 13, 2016, 11:38:02 pm
    SO...
    Protein synthesis is about making proteins from your DNA...

    It takes place in 2 stages - transcription (where DNA is converted into mRNA) and then translation (where mRNA and tRNA combine to make a polypeptide). A bunch of polypeptides make a protein.

    To go into detail;
Transcription: DNA -> mRNA
1. DNA unwinds and unzips
2. RNA polymerase links complementary RNA nucleotides to the unwound DNA – forming an mRNA strand
3. mRNA strand is modified so that it contains only exons (regions that code for proteins)
4. mRNA moves from the nucleus of the cell into the cytoplasm[/li][/list]

Translation: mRNA + tRNA -> polypeptide -> protein
5. mRNA binds to a ribosome
6. tRNA carrying anticodons binds to mRNA’s codons
7. A polypeptide chain is formed until a ’stop’ codon is reached
8. Newly formed polypeptide chain is released into the cytoplasm

It always occurs in this order. If you have faulty or mutated DNA, you'll end up with a different polypeptide produced!

Does this all make sense?

Wow! Aren't you the NSW Bio Lecturer?? Omg can I have an autograph????  8)
Title: Re: Protein synthesis
Post by: Sa1998 on July 14, 2016, 08:12:04 am
Yes this makes so much sense thank you!!!
Title: Re: Protein synthesis
Post by: naomisirmai on July 14, 2016, 10:19:08 am
Wow! Aren't you the NSW Bio Lecturer?? Omg can I have an autograph????  8)

So I've heard!
You can have an autograph if you're lucky :D
Title: Re: Protein synthesis
Post by: naomisirmai on July 14, 2016, 10:20:04 am
Yes this makes so much sense thank you!!!

Ah great, I'm so pleased! Good on you for making sure you understand.
Title: Re: Protein synthesis
Post by: ehatton2016 on July 14, 2016, 12:20:16 pm
Strongly recommend drawing protein synthesis, for example on a whiteboard over and over until it sticks. I hate this section and always get it confused with DNA replication. We did a model using pipe cleaners and pom poms at school, but it was such a wast of time, so much better to draw it.

Hope this is helpful!!
Title: Re: Protein synthesis
Post by: naomisirmai on July 14, 2016, 06:26:14 pm
Strongly recommend drawing protein synthesis, for example on a whiteboard over and over until it sticks. I hate this section and always get it confused with DNA replication. We did a model using pipe cleaners and pom poms at school, but it was such a wast of time, so much better to draw it.

Hope this is helpful!!

Can confirm! Here's my drawing of protein synthesis - make your own in a way that you understand!
Title: Re: Protein synthesis
Post by: CinnamonTea on July 17, 2016, 12:37:36 am
Naomisirimai is spot on offcoarse, the only detail I like to add to enhance my understanding is that transcription occurs in nucleus and translation in the cytoplasm
Title: Re: Protein synthesis
Post by: vox nihili on July 17, 2016, 10:35:42 am
And also to avoid any confusion, the stop codon is not part of the polypeptide but rather of the mRNA
Title: Re: Protein synthesis
Post by: aaron_solomon on July 18, 2016, 06:21:04 pm
can someone please explain to me the relationship between proteins and polypeptides, i know that polypeptides make up proteins but is there any more to that dot point that i should know?
Title: Re: Protein synthesis
Post by: stephanieazzopardi on July 18, 2016, 06:39:26 pm
can someone please explain to me the relationship between proteins and polypeptides, i know that polypeptides make up proteins but is there any more to that dot point that i should know?

Proteins are made up of amino acids bonded together by peptide bonds. A polypeptide consists of two or more amino acids. Therefore a protein is developed from a series of polypeptide chains. And without polypeptides, you wouldn't have a protein. That's how they're related.  :)
Title: Re: Protein synthesis
Post by: jamonwindeyer on July 18, 2016, 06:43:29 pm
Proteins are made up of amino acids bonded together by peptide bonds. A polypeptide consists of two or more amino acids. Therefore a protein is developed from a series of polypeptide chains. And without polypeptides, you wouldn't have a protein. That's how they're related.  :)

OMG aren't you the General Math lecturer?? Can I have an autograph!  8)
Title: Re: Protein synthesis
Post by: stephanieazzopardi on July 18, 2016, 06:52:33 pm
OMG aren't you the General Math lecturer?? Can I have an autograph!  8)

Sorry, I don't give out my snazzy autograph to randoms. Especially the Mathematics lecturer  :)
Title: Re: Protein synthesis
Post by: aaron_solomon on July 18, 2016, 07:59:14 pm
Proteins are made up of amino acids bonded together by peptide bonds. A polypeptide consists of two or more amino acids. Therefore a protein is developed from a series of polypeptide chains. And without polypeptides, you wouldn't have a protein. That's how they're related.  :)

thank you!!! this helped so much!!! also can you please explain sex linkage with examples because I'm not 100% confident with that :)
Title: Re: Protein synthesis
Post by: xorichard on July 20, 2016, 06:33:29 pm
Wow! Aren't you the NSW Bio Lecturer?? Omg can I have an autograph????  8)

Arigatou gozaimasu
Title: Re: Protein synthesis
Post by: stephanieazzopardi on July 21, 2016, 09:35:49 pm

thank you!!! this helped so much!!! also can you please explain sex linkage with examples because I'm not 100% confident with that :)

Blueprint of Life is a pretty hard topic to grasp! You can download my study notes for this topic here: http://atarnotes.com/note/blueprint-of-life-study-notes/
Title: Re: Protein synthesis
Post by: AngelicOnyx on October 10, 2016, 09:56:25 am
Is protein synthesis just another term for polypeptide synthesis? Or do we refer to it as protein synthesis if asked~
Title: Re: Protein synthesis
Post by: Skidous on October 10, 2016, 10:45:02 am
Is protein synthesis just another term for polypeptide synthesis? Or do we refer to it as protein synthesis if asked~
Yes it is another term as chains of polypeptides become proteins. If you have any other questions please see the Biology Question Thread
Title: Re: Protein synthesis
Post by: kavinila on October 12, 2016, 05:18:37 pm
hey guys!
does anyone have some sort of method which helps them differentiate dna replication and peotien synthesis? i get especially confused by translation and transcription ... thanks! :)
Title: Re: Protein synthesis
Post by: studybuddy7777 on October 12, 2016, 07:04:01 pm
hey guys!
does anyone have some sort of method which helps them differentiate dna replication and peotien synthesis? i get especially confused by translation and transcription ... thanks! :)

Hey kavinila!

I think an image will best distinguish these terms!

(https://encrypted-tbn2.gstatic.com/images?q=tbn:ANd9GcSN5K0TrmVehCNi5OClxQ41DdT2IEaNT8frmoPpUdv6LWOytMUpArKvNsa6)

Hope this helps and if it doesn't I will explain it in words :)