Hi wondering what's the best way to determine if a condition is sexlinked dom/recessive/non sex linked Dom/recessive.
Thanks !
First you determine if the condition is dominant or recessive. This can easily be discovered by checking if all affected individuals have at least one affected parent. If the condition skips a generation, it must be recessive and if it is shown to never skip a generation it is dominant.
Then you can move into X-linked and autosomal. You have to do some trial and error here using mental Punnett squares.
If recessive:
X-linked will definitely favour males over females and an affected mother must pass it onto her son. The gender ratios will be roughly equal in autosomal so the key is to try and rule out X-linked by seeing if an affected mother doesn't pass it onto her son.
If dominant:
X-linked will favour females and an affected father must pass it onto his daughter and an unaffected mother cannot have an affected son. As with recessive, proving the condition is autosomal relies on ruling out X-linked, such as the fact that two affected parents can only have an unaffected child if the condition is autosomal.