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November 01, 2025, 01:03:07 pm
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Author Topic: Synthesis of Medicine  (Read 581 times)  Share 

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jackson1234

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Synthesis of Medicine
« on: May 04, 2011, 01:37:34 pm »
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Why is it that when we react ethanoic acid and salicylic acid, we have a relatively lower and slower yield of aspirin,  that compared of reacting salicylic acid and acetic anhydride ? 
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Mao

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Re: Synthesis of Medicine
« Reply #1 on: May 05, 2011, 12:19:46 am »
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acetic anhydride is much more reactive than ethanoic acid.
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rama235

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Re: Synthesis of Medicine
« Reply #2 on: May 26, 2011, 06:56:45 pm »
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its because when using ethanoic acid, the byproduct of water can reverse the reaction, so in the end, there won't be much aspirin. ethanoic anhydride doesn't produce water as a byproduct, so it has a higher production/yield of aspirin
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