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November 01, 2025, 12:52:21 pm
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Author Topic: Drawing a nucleotide  (Read 1163 times)  Share 

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golden

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Drawing a nucleotide
« on: June 10, 2011, 12:39:12 pm »
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When drawing a nucleotide, does it matter which way the phosphate group 'faces'?

For example, these three diagrams have their phosphate groups 'facing' in different ways:

1. http://www.dnareplication.info/dnadoublehelix.php ('faces' down).
2. http://www.biologyreference.com/Mo-Nu/Nucleotides.html ('faces' up) (scroll down).
3. http://bioweb.wku.edu/courses/biol115/Wyatt/Nucleic_Acids/Nucleotides.htm ('faces' sideways).
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Russ

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Re: Drawing a nucleotide
« Reply #1 on: June 10, 2011, 12:45:34 pm »
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All three are correct, the double bond is due to a delocalised electron spread out over that area. It manifests as a P=O double bond, but it can be any of them
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thatricksta

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Re: Drawing a nucleotide
« Reply #2 on: June 10, 2011, 06:00:53 pm »
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Just make sure you dont bond the oxygen again if it already has 2 bonds haha
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stonecold

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Re: Drawing a nucleotide
« Reply #3 on: June 10, 2011, 06:50:04 pm »
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I doubt you will be required to draw a nucleotide/polynucleotide/base pair, but just incase:
-Make sure you know where everything is attached.  i.e. phosphate to sugar, sugar to base, nucleotide to nucleotide (both hydrogen bonding between strands and covelently linked nucleotides within a strand)
-Know that everything (except H-bonds) are condensation reactions
-Make sure you draw DEOXYRIBOSE sugar for DNA.  One of the nucleotides in the link posted above has ribose sugar, which is only in RNA.
-As mentioned above, the double bond in phosphate can be placed anywhere.
« Last Edit: June 10, 2011, 06:52:18 pm by stonecold »
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VivaTequila

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Re: Drawing a nucleotide
« Reply #4 on: June 10, 2011, 10:02:29 pm »
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What are the linkages between the phosphate group and the sugar group called? TSFX just owned me by calling it a phosphodiester linkage, and I thought it was something closer to an ether linkage.

Any insight on this?
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Greatness

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Re: Drawing a nucleotide
« Reply #5 on: June 10, 2011, 10:15:18 pm »
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yeah it's a phosphodiester bond not sure on the logics behind it, but it probs has someting to do with its name...
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