Why are some cancers resistant to the radiation and chemical treatments that would kill healthy cells.
Thanks in advance.
Bellatrix Lestrange
Hi Bellatrix, there might be many reasons why some cancers are radiation resistant. I don't think at a VCE level we really have to explore too much the specifics why this might be the case. However a way in VCE context you might think about it is there may be possible dysfunction of certain signalling molecules involved in the cells intrinsic apoptotic pathway and as a result DNA damaging radiation which otherwise may have triggered cell apoptosis may not cause apoptosis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914062/ here's a review paper exploring some of the ideas involved for interest but really from a VCE perspective just focus on my point above.