Hello AN,
I was just wondering what the best way to answer this question would be:
"A human cell has approximately 25,000 genes and E. coli has approximately 4000 genes. Explain why the number of genes is not an indicator of the size of the genome."
I'm not quite sure if I'm right but I was thinking that the genes in humans are more complex...? So there would be more bases coding for each one?
Or that there may be more alternate forms of genes?
But I'm not sure...
I'm pretty sure that the question isn't asking you to compare the number of genes in a human cell and E.coli, it's asking you why the size of the genome for a species can differ from the number of genes from a cell of that same species.
Based on my understanding I would answer it something like this:
o The genome is the complete set of genes or DNA in an organism.
o While the genome varies between species, all organisms of a single species will share the same genome.
o However, even if the genome is shared between organisms of a single species, not all the genes of that particular genome are inherited by
an organism as there are multiple forms of a single gene (alleles).
o (For example, if a person has blue eyes they will only have the allele for the eye
colour gene that codes for blue eyes as it is recessive. This means that the alleles coding for brown, green or other eye colour will not be present in
a cell of that particular human. However, there are still other humans that will have alleles coding for brown eyes or green eyes. The genome
includes ALL the alleles present in ALL humans and not just one.)
o The genes present in a single human cell or a single E.coli will NOT have a copy of all the multiple forms of a single gene.
o Therefore, the genes of a single cell cannot indicate the size of the genome.
Hope this helps!