Can someone confirm these signal transduction process definitions?

[juntyhee]

Signal Transduction Pathway for Hydrophilic Signals
Reception - Signalling molecule binds onto specific receptor on surface of membrane, which undergoes a conformational change.
Transduction - This activates many secondary messenger molecules, triggering a cascade of events that result in signal amplification.
Cellular Response - This cascade ultimately leads to the induction of a cellular response.

Signal Transduction Pathway for Hydrophobic Signals
Reception - Signalling molecule binds onto specific receptor in the cytoplasm or nucleus.
Transduction - The signal-receptor complex enters the nucleus and binds onto a segment of DNA as a transcription factor.
Cellular Response -  This activates gene expression and leads to protein production in order to carry out a specific response.

[PhoenixxFire]

Signal Transduction Pathway for Hydrophilic Signals
Reception - Signalling molecule binds onto specific receptor on surface of membrane, which undergoes a conformational change.
Transduction - This activates many secondary messenger molecules, triggering a cascade of events that result in signal amplification.

One signalling molecule binding to one receptor activates one secondary messenger molecule - this molecule then activates many others and they activate others. That chain of reactions is called signal cascade and the multiplication of the signal (because 1 molecule activates many, and then each of them activate many) is called signal amplification. They way you've worded this sentence seems to imply that signal amplification is the main purpose of transduction, which it isn't. Moving the signal inside the cell is.

Cellular Response - This cascade ultimately leads to the induction of a cellular response.

Signal Transduction Pathway for Hydrophobic Signals
Reception - Signalling molecule binds onto specific receptor in the cytosolplasm or nucleus.
Transduction - The signal-receptor complex enters the nucleus and binds onto a segment of DNA, acting as a transcription factor.
Cellular Response -  This activateschanges the rate of Transcription factors don't just activate transcription, they can also speed it up or slow it down gene expression and leads to protein production in order to carry out a specific response.