can anyone please explain cellular respiration
Cellular respiration is the process whereby unicellular and multicellular organisms convert chemical energy (glucose, sugars, more complex carbs) into a form of energy that cells can rapidly and conveniently use, the form known as Adenosine Triphosphate (ATP). Now in VCE biology, glucose is the main sugar that is known to be hydrolyzed for energy harvesting.
Glycolysis: What happens?Glucose molecules are broken down via enzymes.
What is released?- 2 pyruvate molecules
- 2NADH molecules
- 2 ATP molecules (however there are 4 produced in total, but 2 are used up in the same reaction, so net production of 2).
Where does it occur? Cytosol of cells.
Does it require oxygen?No. If there is no oxygen available after glycolysis, then the pyruvate molecules will undergo fermentation reactions, in animals lactic acid is produced, and in plants/yeast ethanol and CO2 are produced. However, if there is oxygen available in the cell, then the following reactions will also occur after glycolysis.
Krebs cycle (Citric acid cycle):What happens?In the Krebs cycle, the two pyruvate molecules enter the mitochondria to undergo further reactions. There are two minor stages (not formal) in the krebs cycle, an initial stage where the pyruvate molecules react with CoA (coenzyme A) to produce CO2, NADH and Acetyl CoA. The Acetyl CoA then undergoes further reactions and produces another two CO2 molecules, 3 NADH molecules and 1 ATP molecule and 1 molecule of FADH2. Remember that two molecules of pyruvate are yielded from 1 molecule of glucose.
What is released?- 6CO2
- 8NADH
- 2FADH2
- 2ATP
Where does it occur? Krebs cycle occurs in the mitochondrial matrix (the fluid substance that is enclosed within the inner membrane of the mitochondria)
Does it require oxygen? Yes, hence this is the second step of aerobic cellular respiration, and the following process is the final step of the aerobic pathway.
Electron Transport Chain: What happens?Remember the 'carrier' molecules from the previous pathways? Well the NADH and FADH2 molecules move along to the cristae of the inner membrane (projections of the inner membrane) and they release their electrons and H ions. The electrons 'flow' along the protein molecules embedded within the cristae (known as cytochromes). As these electrons pass along the cytochromes, the hydrogen ions are also being released from the NADH molecules. This means that a concentration gradient is accumulating of H ions, hence the Hydrogen ions need to diffuse (facilitation, since ions are charged and cannot simply diffuse through the membranes) down their gradient. As this occurs, the transmembrane (a protein that is embedded and protrudes through the membrane) enzymes known as ATP synthase simultaneously synthesise ATP molecules as Hydrogen ions diffuse down. This process synthesises approx. 32-34 molecules of ATP, depending on the need and type of cell (muscle cells require 34 as they are involved in more movement and protein contractions as compared to the cells of the stomach). So what happens with the hydrogen ions and the electrons that are being passed down the various cytochromes? Well, lone oxygen molecules await them and accept them, to produce water (H2O).
What is released?- 32-34 ATP molecules
- 8NAD+ (no need to list this)
- 2FAD (no need to list this)
- Water molecules (amount not required)
Does it require oxygen? Yes and it is the last step of aerobic cellular respiration.