Hypervariable regions of DNA (HVRs)

[splash.of.colour]

hi all,

My school uses the Nature of Biology textbook and i was just hoping someone could clarify something for me,

The texbook says that hypervariable regions are "in the non-coding region of mtDNA" (pg 439), but in the glossary, hypervariable regions is defined as "regions of chromosomal DNA [/u] in which great variation exists in unrelated individuals, often due to variation in the number of repeats of short base sequences"

could someone please clarify what hypervariable regions of DNA actually areee? thanksss

[Jenny_2108]

hi all,

My school uses the Nature of Biology textbook and i was just hoping someone could clarify something for me,

The texbook says that hypervariable regions are "in the non-coding region of mtDNA" (pg 439), but in the glossary, hypervariable regions is defined as "regions of chromosomal DNA [/u] in which great variation exists in unrelated individuals, often due to variation in the number of repeats of short base sequences"

could someone please clarify what hypervariable regions of DNA actually areee? thanksss

Hypervariable regions are the segments of DNA which vary greatly between individuals. It can be in DNA or mtDNA

In nuclear DNA, STRs (microsatellites) is used
In mtDNA, the non-coding region is used but less precise due to same maternal lines

[splash.of.colour]

thankyouuu!