Saheh's 3/4 question thread

[pi]

hey all

so I know B cells chill out in the lymph nodes after maturing in bone marrow,
and T cells Mature in the thymus after developing in bone marrow,
where do T Cells hang out?
In the lymph nodes? or just floating around everywhere?

thanks!

In the nodes

[saheh]

Thanks!



Ok couple of qns I found:
What cells recognise non-self cells?
Is it cells the macrophages/dendritic cells
In 2nd line,
And t and b cells in third?

[pi]

Thanks!



Ok couple of qns I found:
What cells recognise non-self cells?
Is it cells the macrophages/dendritic cells
In 2nd line,
And t and b cells in third?

Recognised by professional APCs - ie macrophages, dendritic cells (and B cells)

T and B cells are primarily in the 3rd line of defense - ie. acquired immunity

[saheh]

Ok thanks!

So a macrophage will engulf material detected as foreign, and preset this on their MHC, and then trigger action of t/b cells?

[pi]

Mainly just activate T cells. CD4 T cells can then activate B cells (to become memory or plasma cells) which can then activate more CD8 T cells. Or, the macrophage can activate the CD8 T cells directly too


edit: CD4 T cells = T helper, CD8 T cells = cytotoxic T

[Gazillionaire]

Can someone explain the terms:
fungi, protozoa, vectors, primary host and intermediate host?
Cheers.

[saheh]

Do we need to know mitosis and meiosis in depth?
(like each stage etc? I haven't done unit 1/2))

[pi]

Do we need to know mitosis and meiosis in depth?
(like each stage etc? I haven't done unit 1/2))

Know it well enough to be able to draw it