For anyone who is doing/has done anatomy: Is this enough information to remember for the process of endochondral ossification? I have memorised this summary (and I understand it well too). And if I have gone wrong in any areas, could someone point that out, because I'm probably wrong somewhere.
Endochondral ossification occurs in long bones. Firstly, primary ossification occurs. Firstly, hyaline cartilage takes the shape of the bone. The chondrocytes then begin to multiply, forming the trabeculae lattice. This lattice is weak and it breaks down, and while this is occurring, the perichondrium is differentiating into the periosteum and the endosteum. The periosteum has an inner osteogenic layer, and an outer fibrous layer. The inner osteogeneic layer contains the osteoblasts, which form columns of bone on the outside of the existing bone. While this is occurring, cartilage is constantly being broken down, and an opening forms. At this stage, on the inside of the periosteum, and on the outside of the endosteum, remodeling is occurring, and cartilage is constantly being replaced by bone. The inner cavity forms the medullary cavity. This process first occurs in the diaphysis and then it moves up/down to the metaphysis.
After primary ossification has occurred, secondary ossification occurs. The nutrient artery enters the bone in an oblique way, through the nutrient foreamen. It is pointed away from the growing end of the bone, which means one end of the bone grows first. The nutrient artery brings with it the osteoclasts and the osteoblasts. This allows growth at the ends of the long bones to begin. The hyaline cartilage at the epiphyseal plate is broken down, and is replaced by bone at the metaphysis. This continues, and the bone grows in length.
Once the bone has finished growth, the epiphyseal growth plate disappears, and an epiphyseal line appears. The epiphyseal and metaphysical arteries also anastomose, meaning they are no longer functional end arteries. The only cartilage left is the articular cartilage on the ends of the bone.