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July 09, 2025, 08:54:52 am

Author Topic: In diabetes, where does extra sugar become stored if the cells can't take it in?  (Read 901 times)  Share 

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forchina

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Jayward

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Its not that the cells CANT take it in. its just that their ability to do so becomes compromised, so they are not as efficient at doing so anymore. the sugar surges around the blood and excesses are expelled in urine. The BGL (blood glucose concentration) increase causes damage to numerous parts of the body and if left untreated, can cause loss of limbs and appendages and later, even blindness as sugar quite plainly deposits on everything and stuffs things up.

alondouek

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I'm not sure if you're asking 'where' or 'what', so here's both :P

What: Glucose gets converted to glycogen, which is the stored form of glucose in mammals.

Where: Glycogen is stored in large amounts in the liver and muscle cells, and in small amounts in the glial cells (neuroglia).
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forchina

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Okay another diabetes question - What causes insulin resistance? All the sites I've found say obesity is linked to insulin resistence, but how?

Russ

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Without delving into the biochemical basis for it, which is rather complex, increased body fat requires more insulin production to maintain glucose entry into cells. Increased production of insulin puts a greater demand on the pancreas to produce it and the pancreas can only cope for so long. There will be elevated insulin production initially (with normal blood glucose levels) as the body responds to the increase in body weight. Eventually, the pancreas will begin to decrease production of insulin ("burnout") and blood glucose levels begin to creep upwards. The final stage is when there is low insulin production and high BGLs.