Lethal Genes

[Mct08]

Hello

I was just wondering if anyone had any notes or knowledge of what 'lethal genes' are and whether we need to know about these for the exam?

Thank you

[Sine]

Hello

I was just wondering if anyone had any notes or knowledge of what 'lethal genes' are and whether we need to know about these for the exam?

Thank you

Its not specifically on the study design but if it comes up they will explain it. In short some combinations of alleles will result in offspring unable to survive.

It has come up on past exams but not recently IIRC, I think may be 12-15 years ago.

Also its more so lethal alleles rather than lethal genes.

[vox nihili]

Its not specifically on the study design but if it comes up they will explain it. In short some combinations of alleles will result in offspring unable to survive.

It has come up on past exams but not recently IIRC, I think may be 12-15 years ago.

Also its more so lethal alleles rather than lethal genes.

Important point. No gene is lethal, otherwise we'd all be dead.

[rachid.kam]

lethal genes are basically genes which result in death of a zygote during early stages. For example, in yellow mice,the yellow colour is dominant. But the zygote can only live in the heterozygous form, Yy. Any zygote with YY is unable to survive. as average, for example,two heterozygotes will instead produce a ratio of 2:1 instead of expected 3:1.