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May 29, 2024, 06:48:25 pm
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Author Topic: The Biological Question Thread  (Read 50284 times)  Share 

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TrueLight

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Re: The Biological Question Thread
« Reply #345 on: October 27, 2010, 08:45:27 pm »
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theres no relative change because both the green (eg. healthy) and red (eg. cancer) cDNA have bound to the reference dna
therefore theres not much more or much less of that gene expressed in that cancer...you got them expressed at equal levels. ie. that gene is active in both cell types

they can hybridize equally because theres lots of dna on the chip... so lets say theres 1 million of the same genes on one chip ... 500k of the red labelled cDNA binds and 500k if the green binds too  

« Last Edit: October 27, 2010, 08:48:46 pm by TrueLight »
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golden

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Re: The Biological Question Thread
« Reply #346 on: October 27, 2010, 08:59:39 pm »
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So in a normal case with someone without the cancer, and someone with the cancer, how would the results differ in the microarray as a whole?
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TrueLight

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Re: The Biological Question Thread
« Reply #347 on: October 27, 2010, 09:14:01 pm »
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well you don't know until you do it and then you see which gene is upregulated in cancer and then so it shows you that it might be important in cancer development... and then you do further studies to show what this gene does etc..
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“Who controls the past, controls the future. Who controls the present, controls the past.”
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"Terrorism is the best political weapon for nothing drives people harder than a fear of sudden death."
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“The bigger the lie, the more inclined people will be to believe it”
Adolf Hitler

"Beware the leader who bangs the drums of war in order to whip the citizenry into a patriotic fervor, for patriotism is indeed a double-edged sword. It both emboldens the blood, just

TrueLight

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Re: The Biological Question Thread
« Reply #348 on: October 27, 2010, 09:15:00 pm »
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Russ if you have a better way of explaining it please do!

but i don't think i would be worrying about it... i dont recall learning anything about microarrays in yr 12...
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Completed Bachelor of Science. Majored in Immunology and Microbiology.

“Who controls the past, controls the future. Who controls the present, controls the past.”
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"Terrorism is the best political weapon for nothing drives people harder than a fear of sudden death."
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golden

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Re: The Biological Question Thread
« Reply #349 on: October 28, 2010, 10:14:40 am »
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Outcomes of cultural evolution in the genus Homo include the following with the exception of:
A. the first use of shaped stone objects as tools.
B. the cultivation of crops.
C. the use of written language.
D. the herding of animals.

Can anyone explain why it is D?

Also, is it acceptable to use DNA triplet and DNA codon interchangeably?

Thanks.
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Russ

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Re: The Biological Question Thread
« Reply #350 on: October 28, 2010, 10:38:32 am »
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Quote from: TrueLight on October 27, 2010, 09:15:00 pm
Russ if you have a better way of explaining it please do!

but i don't think i would be worrying about it... i dont recall learning anything about microarrays in yr 12...

If there's a question about it, there'll be plenty of background information supplied. But the general principle is what's important:
DNA is tagged in two colours and added to a well. If you see colour A, then there's lots of DNA A. If you see colour B, there's lots of DNA B. If you see something in between, then there are both.

From that, you can work out which bits of DNA etc. are relevant to certain cells - so it a tumour has extremely low expression of a gene (ie p53 or Rb) you can conclude it's somehow related
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golden

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Re: The Biological Question Thread
« Reply #351 on: October 28, 2010, 10:45:00 am »
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Quote from: Russ on October 28, 2010, 10:38:32 am
Quote from: TrueLight on October 27, 2010, 09:15:00 pm
Russ if you have a better way of explaining it please do!

but i don't think i would be worrying about it... i dont recall learning anything about microarrays in yr 12...

If there's a question about it, there'll be plenty of background information supplied. But the general principle is what's important:
DNA is tagged in two colours and added to a well. If you see colour A, then there's lots of DNA A. If you see colour B, there's lots of DNA B. If you see something in between, then there are both.

From that, you can work out which bits of DNA etc. are relevant to certain cells - so it a tumour has extremely low expression of a gene (ie p53 or Rb) you can conclude it's somehow related

Great answer. Thanks.
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golden

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Re: The Biological Question Thread
« Reply #352 on: October 28, 2010, 11:36:36 am »
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Would we say that after transcription the mRNA leaves the nucleus to go into the cytoplasm or cytosol? Or possibly either can be used?
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Re: The Biological Question Thread
« Reply #353 on: October 28, 2010, 12:05:23 pm »
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Quote from: golden on October 28, 2010, 11:36:36 am
Would we say that after transcription the mRNA leaves the nucleus to go into the cytoplasm or cytosol? Or possibly either can be used?

my teacher says to just say cytoplasm
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Russ

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Re: The Biological Question Thread
« Reply #354 on: October 28, 2010, 12:15:49 pm »
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Cytosol is technically going to be more correct, but cytoplasm is perfectly acceptable (since cytosol is a subset of cytoplasm)

Personally, I'd write cytoplasm
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Allygator

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Re: The Biological Question Thread
« Reply #355 on: October 28, 2010, 01:23:21 pm »
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http://img24.imageshack.us/img24/8376/screenshot20101028at122.png

This is a question from the 2001 VCAA exam that I couldn't understand. I thought the answer would be A but apparently it's B. Can anyone explain to me why?
Thanks :)
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golden

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Re: The Biological Question Thread
« Reply #356 on: October 28, 2010, 01:29:16 pm »
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Quote from: Allygator on October 28, 2010, 01:23:21 pm
http://img24.imageshack.us/img24/8376/screenshot20101028at122.png

This is a question from the 2001 VCAA exam that I couldn't understand. I thought the answer would be A but apparently it's B. Can anyone explain to me why?
Thanks :)

The question implied that one parent was homozygous recessive through the words 'test cross', and mentioned that one parent was heterozygous at both gene loci.
The genes are also unlinked.

If you do the cross you will find that that B is correct.
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Allygator

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Re: The Biological Question Thread
« Reply #357 on: October 28, 2010, 01:36:06 pm »
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oohh, thanks! i misread it :P
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stonecold

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Re: The Biological Question Thread
« Reply #358 on: October 28, 2010, 04:53:05 pm »
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Gotta love Insights attempt at maths on their 2010 exam MCQ10.

Go learn the binomial distribution ffs...
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stonecold

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Re: The Biological Question Thread
« Reply #359 on: October 28, 2010, 05:00:17 pm »
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Mistake, or just me?

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