Enzymes

[panicatthelunchbar]

Hi Guys,

What is an enzyme-substrate complex? Does anyone have a proper definition for it?

Also I know that enzymes can be either intracellular or extracellular. But would I be correct in saying that intracellular enzymes include metabolic enzymes and extracellular enzymes include digestive enzymes (pepsin, trypsin)? Or can both types be either? :/

What are some examples of metabolic enzymes?

Thanks!

[scocliffe09]

Hi Guys,

What is an enzyme-substrate complex? Does anyone have a proper definition for it?

Also I know that enzymes can be either intracellular or extracellular. But would I be correct in saying that intracellular enzymes include metabolic enzymes and extracellular enzymes include digestive enzymes (pepsin, trypsin)? Or can both types be either? :/

What are some examples of metabolic enzymes?

Thanks!

E-S complex is the compound formed when the substrate binds to the active site of the enzyme while the reaction is occurring and being catalysed by the enzyme.
I wouldn't worry too much about which enzymes have to be where. I think that, taking your examples,metabolic enzymes are probably usually located in the cell and digestive usually outside, but for example lysosomes (inside the cell) contain some digestive enzymes - so don't make blanket statements like "digestive enzymes are extracellular".
I don't think you need to know specifics of metabolic enzymes but for example, a group called the hexokinases catalyse the first step of glycolysis, and a whole bunch catalyse the krebs cycle.

[panicatthelunchbar]

Cool, that makes sense now!
Thanks