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March 28, 2026, 10:47:33 am
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Author Topic: aspirin reaction?  (Read 1100 times)  Share 

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Tonychet2

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aspirin reaction?
« on: May 22, 2012, 11:32:40 pm »
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how does aspirin undergo acid-base reaction with NaHCO3? or how does aspirin act as a base?
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amilss

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Re: aspirin reaction?
« Reply #1 on: May 22, 2012, 11:58:08 pm »
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Aspirin would act as an acid

-COOH group on aspirin ----> donates H+, creating -COO- (negatively charged)
The negative charge attracts the Na+ ion, increasing aspirins solubility

The H+ is donated to HCO3-, to form H2CO3, carbonic acid
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Tonychet2

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Re: aspirin reaction?
« Reply #2 on: May 23, 2012, 09:22:44 pm »
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ok that makes sense .. ty

i was confused because i thought the nahco3 was an acid because h2co3 = carbonic ACID??
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AllAboutTheLGs

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Re: aspirin reaction?
« Reply #3 on: May 23, 2012, 09:39:26 pm »
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One thing to add, make sure you draw the charges of COO- and Na+ in the structural formula.
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LukeHigham

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Re: aspirin reaction?
« Reply #4 on: May 24, 2012, 06:05:45 pm »
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Aspirin COOH would react with HCO3- to give bubbles of CO2 and water.

RCOOH + NaHCO3 --> RCOO- + Na+ +CO2 + H2O
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