Biochemistry & Molecular Biology Amino Acid question

[simpak]

I thought it was 'full detail here' (inc structures) as it says on the slide HOWEVER he has never asked about it in any sample exams.
It's not too tricky to learn I managed it very quickly because if you just think about what the steps mean in terms of Chem 2 (eg oxidation is removing hydrogens, hydration is adding a water) and kind of know where stuff is going on the molecule in terms of the bond you're altering during the process it's not too hard.
You don't need to know for the enzyme names though.

[Starlight]

I thought it was 'full detail here' (inc structures) as it says on the slide HOWEVER he has never asked about it in any sample exams.
It's not too tricky to learn I managed it very quickly because if you just think about what the steps mean in terms of Chem 2 (eg oxidation is removing hydrogens, hydration is adding a water) and kind of know where stuff is going on the molecule in terms of the bond you're altering during the process it's not too hard.
You don't need to know for the enzyme names though.

ah ok damn, thanks!

[Starlight]

wondering if I should email him or not to clarify :l

[simpak]

He seems pretty nice, if you don't want to learn it then go ahead!
Or ask on that discussion board.......there is one right?

[Starlight]

He seems pretty nice, if you don't want to learn it then go ahead!
Or ask on that discussion board.......there is one right?

meh i'll learn it, it's just that it wasn't as clear as to whether we had to know the structures like in glycolysis

[simpak]

Hey guys I have a question, when you're writing out glycolysis do you/how do you usually indicate that there are two glyceraldehyde-3-phosphates being fed into the payoff phase from the original glucose fed in to the preparatory phase?  Do you usually just ignore it when showing the sequence from G3P or do you write 2 in front of all your structures from then on?  Just interested to know s:

[claireb]

Hey guys I have a question, when you're writing out glycolysis do you/how do you usually indicate that there are two glyceraldehyde-3-phosphates being fed into the payoff phase from the original glucose fed in to the preparatory phase?  Do you usually just ignore it when showing the sequence from G3P or do you write 2 in front of all your structures from then on?  Just interested to know s:

When I wrote it out "neatly" as a cheat sheet, I put (2) (as in the Lehninger diagram) in front of all the things from G3P but when I have been writing it out trying to memorise, I have left out the twos to make it a bit easier as it does get messy when you have the two G3Ps coming together from step 4 and 5 to form 1,3-Bisphosphogycerate in step 6.

When adding the twos, I wasn't sure how to have an arrow continuing on from the G3P product of step 5 going directly to the product of step 6 instead of writing out (2) G3P + 2Pi again and continuing from there. I hope that makes some sort of sense.

So not 100% sure what to do for the exam, anyone have any ideas?

[simpak]

I know it seems so messy ):  Arghhh, I ceebs writing two for everything!

[Turtle]

I'm just writing the whole thing out in full, as it appears in the lectures.

[Turtle]

Hey for the 2011 exam, for MCQ 13:
Why is the answer not 5, that there is a methyl group in the side chain of one of the residues. I know that only one is basic, but why isn't 5 right also. Leucine has 2 methyl groups in it side chain, and no other residue does?

[Turtle]

Also I thought phospholipids could ready diffuse through the membrane, just not in or out of it? Can someone explain why this is wrong?

[simpak]

Turtle I thought that q was stupid as well; I think maybe because leucine has two methyl groups it's not correct so lysine is the best answer?
And phospholipids can laterally diffuse easily but they can't transverse the membrane (ie can't move from one layer to the next).  So they're basically confined to their own layer in the membrane but they can move freely within that layer, just from side to side only.

[Starlight]

How'd you guys go?

I had a complete mental blank with the kinetics stuff and guessed most of the translation stuff, not too confident.

[simpak]

Ughhhh oh my god. I was running so late. Left my house at 715 this morning and ice was all over my car but the windscreen water was absent entirely so I tried to use the hose to fix it, hose doesn't work. So then I had to go take jugs of water to and from my car to fix this situation. Then I got on the freeway, still all good for time, trying to get to the station which usually takes ten minutes. MUST HAVE BEEN ICY ON THE ROAD EARLIER because some genius crashed into the traffic lights at the very end of the freeway and banked cars back about 4km, and there are no exits to get out so I started FREAKING OUT. After waiting for 35 minutes I finally got to the station 40 minutes later, parked and ran for a train. Got on the train at 820 and was like okay cool I can still make this. Then we got to spencer st station and they waited there for 25 minutes I was like fuck off can anything else make me any more late. Ran all the way to reb from parliament inc the escalator and managed to get there at reading time but I was so frazzled and I kept coughing because I'm like the most unfit person ever so the escalator killed me. So basically I don't remember much, I thought it very cruel of her to ask us something so different without giving practice materials similar to what she wanted to ask us and I feel like I probably made plenty of stupid mistakes because I was so stressed after my shitty morning. THE END, I just needed to rage argh

[Turtle]

I found it pretty good. The enzyme kinetics stuff wasn't great, but I think most likely got half those marks which is good.
And the true/false DNA binding stuff was a little tricky!!