Can someone please check my understanding:
HUMORAL DEFENSE-
-Antibodies on B-cell complex with a complementary antigen.
-Concurrently, the antigen-complementary Th cell becomes activated upon binding with same antigen, releasing interleukin-2.
-Interleukin-2 stimulates B-cell clonal expansion, resulting in the differentiation and proliferation into plasma and memory B-cells.
-Plasma B cells synthesise and secrete immunoglobulins which either deactivate the concerned pathogen, or induce opsonisation, for example.
-Memory B-cells remain present, ready for future exposure.
CELL-MEDIATED RESPONSE:
-Cytotoxic T-cell receptor binds with a complementary antigen which is complexed with MHC I (e.g. infected cells).
-Concurrently, the antigen-complementary Th cell becomes activated upon binding with same antigen, releasing interleukin-2.
-Interleukin-2 stimulates Cytotoxic T-cell clonal expansion, resulting in the differentiation and proliferation into effector and memory Cytotoxic T-cells.
-Upon identification of foreign antigen (complexed with MHC I), cytotoxic T-cells secrete granzyme and perforin to 1) create perforations in the cell's membrane, and 2) induce apoptosis. This consequently kills infected SELF cells which express foreign antigens.
-Memory cytotoxic T-cells remain present, ready for future exposure.
Is this all we need to know about the adaptive immune response?