How accurate is the attached image regarding inflammation and fever? (Neap 2009 answer)
Few questions:
1. Describe one possible form of an effective equine influenza vaccine?
Can it be said that if the viral genome is removed, the virus is attenuated and is unable to infect, but still will induce an immune response?
2. Explain how the vaccine would lead to an immune response in a horse?
This is exactly what I wrote:
The attenuated viruses will be engulfed by phagocytes such as macrophages and the antigenic fragments presented on MHC II markers. Specific helper T cells recognise these markers and become activated, then these helper T cells activate cytotoxic T cells to proliferate into effector and memory T cells. B cells are also activated when they present the same antigen on their MHC II markers to helper T cells and proliferate into plasma and memory B cells.
Their answer is also attached (second image). They have nothing mentioned about Cytotoxic T cells, anyone know why? How would I know not to include T cells in the answer? Is it bad that I actually did? Also, they go on about antibody production and pathogen neutralisation, is this required to be stated in the answer? Because the question says how the vaccine would lead to an immune response, but once again why did they not mention the activity of T cells?