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April 24, 2026, 11:19:00 pm

Author Topic: MHC markers  (Read 880 times)  Share 

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shuurai_uchiha

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MHC markers
« on: June 14, 2016, 08:28:37 pm »
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What are the structural and functional differences between MHC I and MHC II markers?

Gogo14

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Re: MHC markers
« Reply #1 on: June 14, 2016, 09:56:57 pm »
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This is from my understanding, can someone confirm/ correct?:
They are both glycoproteins, but they each have a different quaternary structure.
MHC 1 is present on all cells except RBCs to identify the cell as "human". This allows the cytotoxic T cell to check the cells and kill any that are non self
MHC 2 is only present on B cells and some phagocytes. These markers allow the helper T cells to bind to B cells to release cytokines for cell proliferation in response to an antigen.
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