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March 17, 2026, 06:05:09 pm

Author Topic: Alternative splicing  (Read 1539 times)  Share 

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Justanotherhuman

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Alternative splicing
« on: October 21, 2019, 12:34:02 pm »
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From my understanding, some sections of pre-mRNA can code for both exons and introns. After splicing, mature-mRNA has regions which can act as both introns and exons. This means that the same gene can code for different protein.
I feel that my understanding is lacking, could you clear it up for me please? Also if you could link it to increase in genetic diversity it would be amazing
Thankyou

alanihale

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Re: Alternative splicing
« Reply #1 on: October 21, 2019, 01:20:00 pm »
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After splicing, mature-mRNA has regions which can act as both introns and exons. This means that the same gene can code for different protein.
Post-transcription/mature mRNA won't have introns as the introns were removed as a part of the post-transcription modification. This leaves just the exons.
Alternative splicing is when the exons are reshuffled.
(i.e. if it was originally Exon 1 - Exon 2- Exon 3 in a chain alternative splicing might produce Exon 2- Exon 1 - Exon 3)
This is a suggested reason as to why the body's proteins are so diverse despite the limited amount of DNA present.
Hope this helps!
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